Can
you take OPC-3 or any other of the Isotonix products in soda, juice,
coffee, etc., rather than water?
What is OPC-3?
OPC-3 is a
natural food supplement that is made up of a combination of three very
powerful bioflavonoids known as oligomeric proanthocyanidins, referred
to as OPC. They are grape seed, red wine, and pine bark extracts.
What is a bioflavonoid?
Bioflavonoids are complex
organic plant compounds found mostly in fruits and vegetables. They
function as a co-factor or helper to the body's immune response to
inflammation, allergy, and infection.
What makes OPC-3
different from other pycnogenol products?
OPC-3 offers
three rich sources of OPC that are rated highest in total polyphenol
content averaging 92%. It is totally bioavailable, water-soluble and
delivered the way nature intended it to be, in an isotonic solution.
With the Isotonix formulation, this product is in position to be
absorbed within five minutes. This combination makes OPC-3
the most powerful natural free radical scavenger, anti-aging, and
anti-oxidant product yet discovered.
Is OPC-3 safe?
Absolutely! OPC had been used
for over twenty years throughout Europe. Extensive studies were
conducted and laboratory testing revealed no evidence for human
toxicity, allergic reactions, birth defects, or carcinogenesis.
How long does OPC
remain in the body?
About three days. OPC circulates
through bodily fluids and is held in the collagen for approximately 72
hours before it is gradually eliminated through urine and perspiration.
Why should everyone
take OPC-3?
Free radical damage or oxidative
stress is real. Everyone is subject to it. Free radicals have been
linked directly to premature aging, circulatory disorders, liver
cirrhosis, arteriosclerosis and more. If you do not have adequate
protection from free radicals, you could very likely age faster and
experience health problems you could have avoided. OPC is the most
powerful natural free radical neutralizer and antioxidant discovered
and you get the best of all OPC in OPC-3. This
product should be taken for life. Laboratory studies have shown that
proanthocyanidins enhance the effectiveness of vitamin E some 50 times
as an antioxidant and some 20 times more for vitamin C. OPC-3
inhibits enzymes that cause inflammation. It reduces histamine
production. It restores capillary integrity and improves circulation,
making it a little easier for each cell to get the food it needs. For
females, it has been known to help correct abnormal menstrual bleeding
and cramps.
Why should I be afraid
of free radicals?
Free radicals cause oxidative
damage to cells and tissues. Damage caused by free radicals contributes
to premature aging, the development of stiff joints and wrinkled skin.
Free radical damage also plays a part in the degenerative diseases we
associate with aging, such as liver cirrhosis, atherosclerosis and
others.
Where does the grape
seed extract in the OPC-3 come from?
Grape seed extract comes from
two companies in the USA and Europe. You can imagine that anywhere
there are grapes there will be proanthocyanidin/bioflavonoid extraction
facility. Due to the proprietary nature of our business, the names of
the companies cannot be given out; however, we have found them to be
reputable and have found that they have significant quality control
procedures in place. The extraction process is different from the
process used by the Pycnogenol producers, Horphag Ltd. The process
involves isolating, drying and powdering grape seeds; extracting the
proanthocyanidins using a combination of pressurized hot water, butanol
and acetone; concentrating and drying the compounds. The specific
variety of grape is not known, but it is likely that a spectrum of red
grape varieties is used for extraction. Remember that it is the
extraction process that is selective for flavonoide and can be used on
material from a variety of plant sources (pine bark, bilberries, citrus
rinds).
Is there an elemental
analysis of OPC-3?
We do not have an elemental
analysis on OPC-3, although the individual extracts
are checked for the presence of heavy metals on a lot-to-lot basis. OPC-3
is not a significant source of minerals, but a complex mixture of
literally scores of polyphenolic compounds.
Is there alcohol or
sulfite in OPC-3 from the Red Wine Extract?
The red wine extract that is
used in Isotonix OPC-3 is a completely
non-alcoholic product. The extract is made from the skin of grapes used
to make red wine, but the crushed grapes are not allowed to undergo
fermentation. Therefore, ethyl alcohol is never formed and does not
have to be removed. "Red wine" extract is an inaccurate use of words.
Also, alcohol evaporates on exposure to air. Since OPC-3
is a dried product, it cannot contain alcohol. Sulfites are usually
added as a preservative for finished wine. Sulfite is not added to the
initial grape crush or at any stage of the extraction process.
Are chemicals used in
processing OPC-3?
Water, butanol, and acetone are
used in the extraction process. They are completely evaporated during
processing.
Does OPC-3 contain
beta-carotene?
No.
Does OPC-3 contain
caffeine?
No, it does not, but it may
contain caffeic acid, which is a low molecular weight phenolic
compound. Caffeic acid is isolated along with other polyphenolic
compounds and flavonoids including proanthocyanidins. Caffeine is not
an antioxidant (it does not transfer electrons or hydrogens to
electron-hungry free radicals), but caffeic acid does have documented
antioxidant properties. Coffee (fruit seeds) and tea (Camellia sinensis
leaves) are likely to contain both caffeine and caffeic acid.
Can OPC-3 be taken with
corticosteroids?
Yes, but it is important to understand when to take these products.
When you have an inflammatory condition that is being treated with
corticosteroids (injections or tablets), you should allow at least 4 to
6 weeks while on this therapy to understand what effects these drugs
have on inflammation. If you begin to take OPC-3, this supplement could
confound the results that are being achieved with corticosteroid
treatment. Your doctor will be able to more fully assess the impact of
corticosteroids on your inflammation if you do not take OPC-3 at the
same time, at least for the first month or so. The proanthocyanidins
are not steroids, and they do not exhibit the same mechanism of action
as corticosteroids on inflammatory white blood cells and other cell
types. However, they are antioxidants and are able to scavenge oxygen
and nitrogen free radicals, which cause considerable cell and molecular
damage. Proanthocyanidins can inhibit the tissue-remodeling enzymes
secreted by inflammatory white blood cells and minimize tissue
disruption. Additionally, the proanthocyanidins have been found to
inhibit an enzyme called inducible nitric oxide synthase (iNOS) that
generates nitric oxide and contributes to damage associated with
uncontrolled inflammation. The proanthocyanidins are also known to
block the synthesis and secretion of histamine which can cause tissue
swelling associated with inflammation. When you start taking OPC-3,
please inform your doctor.
What kind of side
effects can we expect during the first weeks of using OPC-3?
Reported complaints - especially
with saturation dosing - include headache, gastric discomfort,
generalized itching, ankle swelling, facial flushing, and occasional
dizziness. These are usually mild, self-limiting and subside within a
day or two.
Can you take OPC-3 or
any other of the Isotonix products in soda, juice, coffee, etc., rather
than water?
It is not recommended. In order
to keep the products in an isotonic form and to achieve the maximum
delivery time it needs to be taken on an empty stomach with 2 oz. of
water per capful. To mix the products with anything else slows down the
delivery time; also the percentage of uptake may be lessened.
| The Food and Drug Administration has not evaluated
these statements. |
| This product is not intended to diagnose, treat,
cure, or prevent any disease. |